I need help with iexplorer.exe error

Hello,
I recently purchased a brand new comp...only issue i have with it is that everytime i try and open my work email server i get the following error message and the window closes. I am not overly computer savy so an answer that would suit an ignoramus such as myself would be appreciated. I am using Vista home for the first time.

Microsoft Visual C++ Runtime Library

Runtime error!
Program: C:\Program Files\Internet Explorer\iexplore.exe

This application has requested the Runtime to terminate it in an usual way. Please contact the applications support team for more information.

Cheers in advance