I am unable to open the computer app or control panel

Hello, I am unable to do anything on my pc . I tried using r kill which worked fine and then I used Malwarebytes. But on installing it my pc is just restarting more than a couple of times and at last it said that it won't install on my computer.
Can you please help me
After I downloaded combofix , it is showing an error dialogue box and a note
"You may be infected with file patching virus 'Virut' "