USB Port nad Sandisk Space not opening files

My Toshiba PC developed a problem lately, I can't access my file, if I connect a flashdrive, USB cable or a Sandisk card reader, it wouldn't even show up, and each time I connect a USB cable to a phone, it only charges it and doesn't connect to the phone media, and this is not from the phone settings cause I alread tried different phones and enabled the connect to USB settings, and each time I try different flashdrives, it shows a light on it, but it doesn't show the flashdrive on my PC, Please I'd appreciate a helpful reply.