It might be connected with Internet Browser Issue, in this case make next steps:
If attempting to open a PDF file within your computer's Internet browser by clicking on a hyperlink, you may encounter an error stating the PDF file cannot open. The error occurs when your Internet browser is missing the plug-in component for opening PDF files within the browser. The error also occurs when a PDF file is corrupt.
During working with .pdf file you probably might been have Blank White Screen in your PDF, it yes, see instruction how to get rid of it:
Another problem you may encounter while trying to open a PDF file is a blank white screen after clicking on the PDF's link within your browser. The problem is related to a missing ActiveX component for opening PDFs, if using Microsoft Internet Explorer or a missing plug-in if using another type of browser--Firefox, Netscape or other browser. The problem also occurs if your computer's PDF reader is not launching properly or is already running as a background process.