Adobe Reader Error 0:104

One of my users is having a strange issue. When she tries to open a PDF file from within Internet Explorer 8 using Adobe Acrobat Reader X (latest version) it pops up a small grey error windows saying:

There is a problem with Adobe Acrobat/Reader. If it is running, please exit and try again. (0:104)

Then the user hits ok and its just a grey screen. Ive went into addons and made sure all the helper objects are enabled for Adobe, even disabling them all gives the same result.

Now if the user tries to access the file like 10x, eventually it will open up but this keeps happening. Even reinstalled the application and same outcome.

Any ideas?