You can try using your other recovery methods such as your phone number if you registered one. See this article which provides different methods to recover a Facebook account. If your account is locked, here's another article with recommendations on how to unlock it.
In case you still can't access your Facebook account and that your email is still required to get your account back, the best thing you can do is to try recovering your email account. You can find the recovery steps here for Gmail - Yahoo - and Outlook/Hotmail.