Pupups/with pop up blocker on.

Hello,
So a few weeks ago I somehow downloaded a programe called MIRAR. I then started having advertisment pop ups, eventhought I have my pop up blocker on the highest level. I started getting others like "we couldnt not find........ file" So I went in and uninstalled the Mirar. Well nothing changed. I looked the program up and the websited said that its one of the most difficult to get rid of. Its an adware and it installs programs with out your permission. I had mc afee on my computer before and after this happened. The adware has attached itself to all kinds of files. Please help me get rid of it without having to take it to a professional. If you need more info about wahts going on write me back what ever it takes...by the way its my bf computer and i messed it up so please please help