Black Screen

Hello,
I have contracted a virus on my pc which runs windows vista i tried to use mcafee to get rid of it but they still remained. I was able to use my computer a for two day s but this morning it showed once I logged in i got a blackscreen with some pop-ups from the virus about Microsoft office not working. It also brought up a window that said an unauthorized change had been made to windows. It let me bring up the internet for more information but cannot find the server of the sight it brings up. DOes anyone know this virus or have a possible solution? Thank you for your time.