XP will not even boot in safe mode

Hello, I've read through this thread and can't find a solution. A few months ago I picked up an Optical mouse from Wallyworld, (Onn wired optical). It would not install with wizard and ended up going through safe mode for it to work. Since then I would get "Found new hardware" message. If I opened the wizard, it would sit and search for hours with no install. The other day the computer would get to the logo page and hang up, sometimes it would shut itself down. I tried safe mode, which only gave me the partition/driver list. Other selections would not complete the boot. I tried the F8, 9, 10 and 11 keys, no joy. I have even tried booting with the original XP CD, but I get the same responses. Its the same with the new mouse unplugged. Any ideas?