Multi problems with Virus

Hello,

Okay here is what I am experiencing. I had a plain as day virus, some antivirus pro 2010 on my computer, I could not access task manager, add/remove programs, registry, command prompt. Downloading anti virus software would not open after downloads. So I pulled the hard drive and ran as a slave in another computer. I ran AVG and Malwarebytes. It cleared many things, but when I reinstalled hard drive back in to original computer, .exe files would not open and gpedit.msc will not either and still all the same problems from above. I am at a lost, suggestions??