My desktop is not responding.

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Registration date
Saturday October 27, 2012
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Wednesday December 19, 2012
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December 20, 2012
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Hello,
Brother, last week i have uninstalled my antivirus from that all my softwares get crashed so yesterday i installed mcfee antivirus and restarted it and it get opened till the wallpaper the icons and task bar will getting opened after that i can't even able turn it off ,can't able restart or turn it off by cpu its not working m not getting what is the problem now what to do, i have some important notes in it .


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Thursday November 1, 2012
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November 1, 2012

either you did not shut down well.good day
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Wednesday December 19, 2012
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December 20, 2012
6
Try to boot your system into Safe mode:

Restart your computer if it is powered on.
Press and hold F8 key for 3 seconds after your computer initially powers on.
Once you see the Advanced Boot Options menu (or hear a beep) you can stop.
Use the up/down arrow keys to highlight your selection.
Select Safe Mode with Networking and press Enter
You should see drivers loading, this may take a few moments.
You should then be at the Welcome Screen.

Logon to your computer using an account with Administrator privileges. Now you should download Intel Software Partner Reginout, install, update then do a scan of your system in safe mode, to make sure it is indeed clean!
Once the scan is done delete anything it finds.
Then simply reboot your PC to see if your issue has been resolved!