Pen drive not found in my computer

Hello, Sir i need your suggestion.on19th January when i was scanning E/:drive pluging my pen drive scan stop suddenly then i cancel scan and try again to scan but it doesn't work and shows defender not responding then i proceed to close the program and message comes like wait still response .i wait for 30 mins but get no response then i close the program thereafter pen drive is not found in MY COMPUTER.Please give me some suggestion so that i can get it.
Thanking You

Haresshtullah