No beeps

Hello,
I have an asus A8v-vm motherboard, I haven't used my desktop for a couple of weeks went too turn it on last night, all the fans kicked in but no boot up,no beeps etc the only way i can turn it off is at the mains, i have removed the ram no beeps,i have changed the battery nothing!,i have swapped video cards still nothing, i suspect that my motherboard my have died,i have treid disconnecting all cables but still the fans will run but nothing else, Any clues Guys?oh i am using windows op system,one of my diskdrives works but not the other soz what i means is my dvd drive the tray will open but not load and my other data driver won't open at all.