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Ya, what software are you using? save option frequently disabled in all Adobe softwares, I experienced that before...the save option disabled in more than 12 hours, I can edit and make my works but became useless because I cannot save...later then I found out that the Adobe Acobat and Reader updated that's why save option became disabled. This problem may be avoided if you use the updated and latest Adobe Reader and Acrobat. Anyway it will be enable after the update so don't worry.