If you have been able to close out using the Task Manager, were you able to successfully reset your Internet Explorer settings as Jack detailed in his first response? This is the first step to try in order to repair the problem.
You can also try running Internet Explorer in No Add-on Mode. This should help cut back on load times. To do so click the Start button, click All Programs, click Accessories, click System Tools, and then click Internet Explorer (No Add-ons).
Let us know what happens!
IE Outreach Team